We use cookies to help provide you with the best possible online experience. Please read our Privacy Policy for information about which cookies we use and what information we collect on our site. By continuing to use this site, you agree that we may store and access cookies on your device.
One More Step to Finalize Your Registration
An activation link has been sent to your email address.
Please check the email and activate your account now. It might take few minutes to get the email.
If you did not find it, please check your spam box.
Having problem receiving the email? Send again
Still cannot receive? Contact us
Email :PharmaSources@imsinoexpo.com
Whatsapp :+86-13621645194
Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia
Sample Provided: no
Photon Cross-Correlation Spectroscopy (PCCS) | Particle Size and Stability of Nanosuspensions from 0.5 nm to 10,000 nm
In general, the acquisition of scattered light intensities of particles under thermal motion is deployed for nanoparticle characterisation (principle of dynamic light scattering (DLS)). The method known as Photon Correlation Spectroscopy (PCS) applies auto-correlation of scattered light intensities in order to determine particle size distribution. However, this conventional technology requires extremely diluted samples in order to deliver meaningful results.
NANOPHOX brings Photon Cross-correlation Spectroscopy (PCCS) to life, which allows for nanoparticle size analysis in turbid suspensions and emulsions ranging from 0.5 nm to 10,000 nm at up to a hundred times higher solid contents. The outstanding technological feature of NANOPHOX is the acquisition of two separately induced scattered light intensities which then are cross-correlated. This allows for robust measurement even at higher sample concentrations. In addition to size, the aggregation or sedimentation behaviour of nanosuspensions (i.e. stability) may be analysed. Typical applications comprise e.g., polymer emulsions, colloidal silica, inks and research on nanodispersions in general.
PCCS advantages
Robust method for research, development and quality control
Concentration independent particle characterisation by elimination of multiple scattering effects
Extension of conventional PCS provides concurrent measurements of particle size and stability in opaque suspensions and emulsions
Easy sample preparation without undesired dilution series
Insensitive to sample contamination
No required cleanroom conditions
Direct measurement of stability, agglomeration and sedimentation of slightly charged (electro-steric stabilised) to uncharged (steric stabilised) particles of turbid samples
Analysis of special effects such as particle-particle interactions and changes in viscosity in high-concentrated samples
High sensitivity for changes in size and measurement of bimodal distributions
Solid-state measuring method for in-situ observation of changes in stability or size, e.g. growth and crystallisation processes
Wide concentration range by PCS and PCCS united
NANOPHOX – Nanoparticle Measurement in Primary Condition
As a professional pioneer of PCCS we are offering the first table top instrument based Photon Cross-Correlation Spectroscopy (PCCS). With this we consequently follow our strategy of developing innovative instruments which measure the sample as close as possible to its original state. The NANOPHOX system together with its powerful PAQXOS control and evaluation software is fully compliant with FDA requirements and 21 CFR Rule 11.